WebNov 19, · Verapamil. This is a drug normally used to treat high blood pressure. It appears to disrupt the production of collagen, a protein that might be a key factor in the .A patch made of human or animal tissue or a synthetic material is placed to cover the defect. Treatment for Peyronie’s Disease Dr. When used early in the disease process, penile traction therapy prevents length loss and minimizes the extent of curvature that occurs. Traction therapy may also be used in the chronic phase of the disease, combined with other treatments or after surgery for a better outcome. Injection Therapy for Peyronie’s Disease Doctors sometimes treat Peyronie’s disease by injecting drugs directly into the plaque.Web Peyronie’s disease is the development of scar tissue inside the penis that causes penile curvature, circular or hourglass deformity, shortening of the penis, pain . WebDec 2, · Peyronie’s disease is a disorder in which the penis bends or curves due to plaque, or lumps, that form inside the penis. Depending on where the plaque is located, . WebNov 5, · Peyronie’s disease (PD) is manifested by localized fibrous inelastic scars in the tunica albuginea and cause palpable penile plaque, abnormal penile curvature, .Surgery Plication of the penis Enlarge image Close Plication of the penis Plication of the penis During plication of the penis, an artificial erection is created from either injection of a saltwater solution or selected medications. The procedure straightens the penis and allows the man to keep an erection, but it does cause the erection to be a little shorter. Most men with Peyronie’s disease cannot identify or recall a traumatic event that precipitated the condition. Medications include: Collagenase. Interferon also has been shown to reduce penile pain in men with Peyronie’s disease.